瞿昆， 男，博士，中国科学技术大学生命科学学院教授、博士生导师。长期从事生物信息学，系统生物学，基因组学和遗传学等领域的研究。在New England Journal of Medicine, Nature, Nature Methods, Nature Biotechnology,  Cell, Cell Stem Cell, Molecular Cell, Developmental Cell, Cell Systems, Genome Research, Genes and Development等国际学术期刊上共发表论文38篇，5年内Google学术引用超过1800次，总影响因子超过400，H-index 19。目前担任PNAS，Nature Protocol等杂志的审稿人。

教育和研究经历：

1999-2004年中国科学技术大学化学物理系，获学士学位

2004-2010年美国印第安纳大学化学系，获物理化学博士学位

2009-2010年美国希望之城，贝克曼癌症研究中心，生物信息学专家

2010-2016年美国斯坦福大学医学院，生物信息高级研究员，中心主任

2016年至今中国科学技术大学生命科学学院，教授，博士生导师

获奖情况：

ORISE Fellowship 2007

主要研究兴趣：

1. 个性化医疗，肿瘤的个性化调控机制

2. 生物大数据分析，云计算基础上的生物信息系统分析软件的开发和应用

3. 转录因子，非编码RNA 和表观遗传修饰对基因表达的调控作用和机制

代表性论文：（*共同一作）

1. K. Qu*, S. Garamszegi*, F. Wu*, et al, J. Mesirov “Integrative genomic analysis by interoperation of bioinformatics tools in GenomeSpace”, Nature Methods, 2016, Jan 18. doi: 10.1038/nmeth.3732.

2. K. Qu*, L. Zaba*, P. Giresi, et al, H. Chang “Individuality and dynamics of personal regulomes in human T cells”, Cell Systems, 1:51-61, 2015 (Previewed in Cell System)

3. Y. Wan*, K. Qu*, Q. Zhang, R. Flynn, O. Manor, Z. Ouyang, J. Zhang, R. Spitale, M. Snyder, E. Segal and H. Chang “Landscape and variation of RNA secondary structure across the human transcriptome” Nature, 505:706-9, 2014 (Highlighted in Nature News & Views)

4. V. Lopez-Pajares, K. Qu, et al, P. Khavari “A LncRNA-MAF/MAFB Transcription Factor Network Regulates Epidermal Differentiation”, Developmental Cell, 32(6), 693-706, 2015 (Cover Article, Previewed in Developmental Cell)

5. C. Benitez, K. Qu, et al, S. Kim “An Integrated Cell Purification and Genomics Strategy Reveals Multiple Regulators of Pancreas Development”, PLoS Genetics, Oct. 16, 2014

6. J. Quinn, I. Ilik, K. Qu, P. Georgiev, et al., H. Chang “Revealing long noncoding RNA architecture and functions using domain-specific chromatin isolation by RNA purification”, Nature Biotechnology, 32:933-940, 2014

7. P. Batista*, B. Molinie*, J. Wang*, K. Qu, et al., H. Chang “m6A RNA Modification Controls Cell Fate Transition in Mammalian Embryonic Stem Cells”, Cell Stem Cell, 15(6), 707-719, 2014

8. O. Wapinski*, T. Vierbuchen*, K. Qu, et al., H. Chang, and M. Wernig “Hierarchical mechanisms for transcription factor-mediated reprogramming of fibroblasts to neurons” Cell, 155(3), 2013

9. Y. Wan, K. Qu, Z. Ouyang, and H. Chang “Genome-wide mapping of RNA structure using nuclease digestion and high-throughput sequencing” Nature Protocols, 8(5):849-69, 2013

10. N. Rapicavoli, K. Qu, et al., H. Chang “A mammalian pseudogene lncRNA at the interface of inflammation and anti-inflammatory therapeutics” eLife, July 23, 2013

11. X. Bao, J. Tang, V. Lopaz-Pajares, S. Tao, K. Qu, G. Crabtree, P. Khavari “ACTL6a Enforces the Epidermal Progenitor State by Suppressing SWI/SNF-Dependent Induction of KLF4” Cell Stem Cell, 12(2):193-203, 2013

12. M. Kretz, D. Webster, C. Chu, Z. Siprashvili, A. Zehnder, K. Qu, et al., H. Chang, and P. Khavari “Control of Somatic Tissue Differentiation by the Long Non-Coding RNA TINCR” Nature, 493(7431):231-5, 2013 (Faculty 1000)  

13. R. Flockhart, D. Webster, K. Qu, et al., P. Khavari “BRAFV600E remodels the melanocyte transcriptome and induces BANCR to regulate melanoma cell migration” Genome Research, 22(6):1006-14, 2012 (Highlighted in Nature Reviews Cancer)

14. Y. Wan, K. Qu, Z. Ouyang, et al., E. Segal, H. Chang. “Genome-wide measurement of RNA folding energies” Molecular Cell, 48:1-13, 2012 (Faculty 1000)

15. A. Bhaduri, K. Qu, et al., and P. Khavari. “Rapid Identification of Nonhuman Sequencing in High Throughput Sequencing Data Sets” Bioinformatics, 28(8):1174-5, 2012 (Faculty 1000)

16. N. Gomez-Ospina, A. Chang, K. Qu, A. Oro. “Translocation Affecting Sonic Hedgehog Gene associated with Basal Cell Carcinomas” The New England Journal of Medicine, 366:2233-2234, 2012

17. C. Chu, K. Qu, F. Zhong, S. Artandi, H. Chang. “Genomic maps of lincRNA occupancy reveal principles of RNA-chromatin interactions” Molecular Cell, 44(4), 667-678, 2011 (Cover Article, Highlighted in Nature Reviews Genetics and Nature Methods, Faculty 1000)

18. S. Marro, Z. Pang, N. Yang, M. Tsai, K. Qu, et al., M. Wernig “Direct Lineage Conversion of Terminally Differentiated Hepatocytes to Functional Neurons” Cell Stem Cell, 9(4) 374-382, 2011 (Cover Article, Faculty 1000, and Highlighted in Nature Biotechnology)

19. K. Qu, A. Yesnik, P. Ortoleva. “Alternative splicing regulatory network reconstruction from exon array data” Journal of Theoretical Biology, 263: 471-480, 2010

20. K. Qu, P. Ortoleva, “Understanding stem cell differentiation through self-organization” Journal of Theoretical Biology, 250(4): 606-20, 2008

21. K. Qu, A. Haidar, J. Fan, L. Ensman, K. Tuncay, M. Jolly, P. Ortoleva. “Cancer Onset and Progression: A Genome-Wide, Nonlinear Dynamical Systems Perspective on Onconetworks”. Journal of Theoretical Biology, 246: 234-244, 2007

Google学术页面:http://scholar.google.com/citations?hl=en&user=2CdOi4EAAAAJ

实验室网页：http://qulab.ustc.edu.cn/

ResearcherID: http://www.researcherid.com/rid/G-3359-2012

招生招聘：

实验室招聘生物信息学、计算生物学，免疫和分子生物学等相关背景的博士后和特任（副）研究员，待遇从优。同时热忱欢迎感兴趣的本科生前来攻读博（硕）士学位。

联系方式：qukun@ustc.edu.cn