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王育才,男,教授,博士生导师2005年于中国科学技术大学获得学士学位;2010年于中国科学技术大学获得博士学位;20111月起先后于圣路易斯华盛顿大学生物医学工程系、佐治亚理工学院生物医学工程系及芝加哥大学James Franck研究所从事博士后研究。2015年回到中国科学技术大学生命科学学院任教。

多年来一直从事纳米材料在癌症治疗及成像领域的研究,在国际学术期刊发表研究论文60余篇,引用次数超过3000余次,H-index33,还为Advanced Functional MaterialsMacromolecular Bioscience撰写邀请综述,并为Nature Materials撰写论文评论。

主要研究兴趣:

1.肿瘤诊断与治疗

2.纳米药物

招生招聘:

1.实验室高薪诚聘特任副教授、特任副研究员,同时招聘具有药剂学、细胞和分子生物学、免疫学、高分子科学、生物材料、纳米生物医学等研究背景之一的博士后研究人员。

2.欢迎具有生物学、化学或药学等背景的本科生报考实验室的研究生,并欢迎“985”高校具有推荐免试研究生资格的优秀学生到实验室攻读博士学位,实验室负责差旅费用,安排实地了解和面谈。

发表论文(#为第一作者,*为通讯作者):   

2017

1.J. Yi,#Y. C. Wang,*,# Y. Jiang, I. Jung, W. Liu,  V. Andrade, R. Xu, R. Parameswaran, I. Peters, R. Divan, X. Xiao, T. Sun, Y. Lee, W. Park,* B. Tian,* Calcite Heterostructures for Dynamic and Deformable Mineralized Matrices. Nature Communications, 2017, accepted

2.D. Li,# G. Zhang, # W. Xu, # J. Wang, Y. C. Wang,* L. Qiu, J. Ding,* X. Yang,* Investigating the Effect of Chemical Structure of Semiconducting Polymer Nanoparticle on Photothermal Therapy and Photoacoustic Imaging. Theranostics, 2017, accepted

3.W. Jiang,# J. L. Wang, J. B. Yang, Z. W. He, G. Q. Zhang, F. Huang, X. C. Zhou, L.F. Yan,* X. Z. Yang,*Y. C. Wang*, and J. Wang, Acidity-triggered TAT-presenting nanocarriers augment tumor retention and nuclear translocation of drugs. Nano Research, 2017, accepted

4.J. Chen,# S. Li, Y. Zhang, W. Wang,X. Zhang, Y. Y. Zhao,Y. C. Wang,*H. Bi,*A Reloadable Self-Healing Hydrogel Enabling Diffusive Transport of C-Dots Across Gel-Gel Interface for Scavenging Reactive Oxygen Species. Advanced Healthcare Materials, 2017, accepted, DOI: 10.1002/adhm.201700746

5.Y. N. Xia,# J. Z. Shen, H. Alamri, N. Hadjichristidis, J. P. Zhao,*Yucai Wang,* and Guangzhao Zhang, Revealing the Cytotoxicity of Residues of Phosphazene Catalysts Used for the Synthesis of Poly(ethylene oxide). Biomacromolecules, 2017, 18, 3233-3237

6.S. Li,# F. Wang,#,* J. Chen, X. Zhang, Y. C. Wang,* J. Liu,* Dipole Orientation Matters: Longer-circulating Choline Phosphate than Phosphocholine Liposomes for Enhanced Tumor Targeting. ACS Applied Materials & Interfaces, 2017, 9, 17736,

7.Y. Zhu, C. Sun,a S. Shen,a M. I. U. Khan, Y. Zhao, Y. Liu, Y. C. Wang,* J. Wang A Micellar Cisplatin Prodrug Simultaneously Eliminates both Cancer Cells and Cancer Stem Cells in Lung Cancer. Biomaterials Science, 2017, accepted, DOI: 10.1039/c7bm00278e (Invited contribution as one of the Emerging Investigators in Biomaterials)

8.J. Chen, J. Ding,*Y. C. Wang, J. Cheng,* S. Ji, X. Zhuang, X. Chen* Sequentially Responsive Shell-Stacked Nanoparticles for Deep Penetration into Solid Tumors, Advanced Materials, 2017, accepted, DOI: 10.1002/adma.201701170

9.S. Shen,# H. Li,# K. Chen, Y. C. Wang, X Yang,Z Lian, J Du,* J. Wang* Spatial Targeting of Tumor-Associated Macrophages and Tumor Cells with a pH-Sensitive Cluster Nanocarrier for Cancer Chemoimmunotherapy, Nano Letters, 2017, accepted, DOI: 10.1021/acs.nanolett.7b01193

10.M. Guo, H. Xiang, Y. Wang, Q. Zhang*, L. An, S. Yang, Y. Ma, Y. C. Wang, J. Liu* Ruthenium Nitrosyl Functionalized Graphene Quantum Dots as an Efficient Nanoplatform for NIR-light-controlled and Mitochondriatargeted Delivery of Nitric Oxide Combined with Photothermal Therapy. Chemical Communications, 2017, 53, 3253-3256

11.H Huang, H Shi, J Liu, Y Min, Y. C. Wang, A. Z. Wang, J. Wang and Y. Liu*. Co-delivery of all-trans-retinoic acid enhances the anti-metastasis effect of albumin-bound paclitaxel nanoparticles. Chemical Communications, 2017, 53, 212-215

12.Y. Wang, K. Uetani, S. Liu, X. Zhang, Y. C. Wang, P. Lu, T. Wei, Z Fan, Jing Shen, H. Yu,* S. Li, Q. Zhang, Q. Li, J. Fan, N. Yang, Q. Wang, Y. Liu, J. Cao, J. Li, W. Chen*, Multifunctional Bionanocomposite Foams with a Chitosan MatrixReinforced by Nanofibrillated Cellulose. ChemNanoMat, 2017, 3, 98-108.

2016

13.M. Zhang*, S. Li, X. Yan, Z. Zhou, M. L. Saha, Y. C. Wang*, P. J. Stang*. Fluorescent Metallacycle-Cored Polymers via Covalent Linkage and Their Use as Contrast Agents for Cell Imaging. Proceedings of the National Academy of Science, 2016, 113, 11100-11105

14.H. X. Wang, Z. Q. Zuo, J. Z. Du, Y. C. Wang*, R. Sun, Z. T. Cao, X. D. Ye, J. L. Wang, K. W. Leong*, J. Wang*. Surface Charge Critically Affects Tumor Penetration and Therapeutic Efficacy of Cancer Nanomedicines. Nano Today, 2016, 11, 133-144

15.Z. T. Cao, Z. Y. Chen, C. Y. Sun, H. J. Li, H. X. Wang, Q. Q. Cheng, Z. Q. Zuo, J. L. Wang, Y. Z. Liu, Y. C. Wang*, J. Wang*. Overcoming Tumor Resistance to Cisplatin by Cationic Lipid-Assisted Prodrug Nanoparticles.Biomaterials, 2016, 94, 9-19

16.Y. Jiang#, J. C. Souza#, R. Wong#, Z. Luo, D. Isheim, X. Zuo, A. Nicholls, I. Jung, J. Yue, D. Liu, Y. C. Wang, V. De Andrade, X. Xiao, L. Navrazhnykh, D. Weiss, X. Wu, D. Seidman, F. Bezanilla*, and B. Tian*.Heterogeneous Silicon Mesostructures for Lipid-Supported Bioelectric Interfaces.Nature Materials, 2016, 15, 1023-1030

17.J. Zimmerman, R. Parameswaran, G. Murray, Y. C. Wang, M. Burke, B. Tian*. Cellular uptake and dynamics of unlabeled free standing silicon nanowires. Science Advances, 2016, 2, e1601039

18.J. Wang, Y. Liu, Y. Ma, C. Sun, W. Tao, Y. C. Wang, X. Yang*, J. Wang. NIR-Activated Super-Sensitive Drug Release using Nanoparticles with A Flow Core. Advanced Functional Materials, 2016, 26, 7516-7516

19.Z. Q. Zuo, K. G. Chen, X. Y. Yu, G. Zhao, S. Shen, Z. T. Cao, Y. L. Luo, Y. C. Wang, J. Wang*. Promoting Tumor Penetration of Nanoparticles for Cancer Stem Cell Therapy by TGF-β Signaling Pathway Inhibition. Biomaterials, 2016, 82, 48-59

20.N. Q. Zhou, L. J. Tian, Y. C. Wang, D. B. Li, P. P. Li, X. Zhang, H. Q. Yu*. Extracellular Biosynthesis of Copper SulfideNanoparticles by Shewanella Oneidensis MR-1 as aPhotothermal Agent. Enzyme and Microbial Technology, 2016, 95, 230-235

21.D. Li, J. Wang, Y. Ma, H. Qian, D. Wang, L. Wang, G. Zhang*, L. Qiu*, Y. C. Wang, X. Yang*. A Donor-Acceptor Conjugated Polymer with Alternating Isoindigo Derivative and Bithiophene Units for Near-Infrared Modulated Cancer Thermo–Chemotherapy. ACS Applied Materials & Interfaces, 2016, 8, 19312–19320

2015

22.Z. Luo#, Y. Jiang#, B. Myers, D. Isheim, J. Wu, J. Zimmerman, Z. Wang, Q. Li, Y. C. Wang, X. Chen, V. P. Dravid, D. N. Seidman, B. Tian*. Atomic Gold–Enabled Three-Dimensional Lithography for Silicon Mesostructures. Science, 2015, 348, 1451-1455.

23.J. Zimmerman, M. Murray, Y. C. Wang, J. Jumper, J. Austin, B. Tian*, Free-Standing Kinked Silicon Nanowires for Probing Inter-and Intracellular Force Dynamics. Nano Letters, 2015, 15, 5492-5498.

24Y. C. Ma, J. X. Wang, W. Tao*, C. Y. Sun, Y. C. Wang*, D. D. Li, F. Fan, H. S. Qian, X. Z. Yang*.Redox-Responsive Polyphosphoester-Based Micellar Nanomedicines for Overriding Chemoresistance in Breast Cancer Cells. ACS Applied Materials & Interfaces, 2015, 7, 26315-26325